Last Updated on May 13, 2023 by admin
Buy Imanib 400mg Tablet Online
About Imanib 400mg Tablet
Imatinib mesylate (400mg)
Imanib 400mg Tablet belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor.
Imanib 400mg Tablet should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
USES OF IMANIB TABLET
- Blood cancer (Chronic myeloid leukaemia)
- Blood cancer (Acute lymphocytic leukemia)
- Gastrointestinal stromal tumour
BENEFITS OF IMANIB TABLET
- In Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Imanib 400mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
SIDE EFFECTS OF IMANIB TABLET
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Imanib
- Edema (swelling)
- Muscle cramp
- Musculoskeletal (bone, muscle or joint) pain
- Abdominal pain
HOW TO USE IMANIB TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Imanib 400mg Tablet is to be taken with food.
HOW IMANIB TABLET WORKS
Imanib 400mg Tablet is an anti-cancer medication. A protein enzyme, bcr-abl tyrosine kinase, responsible for the growth of abnormal proliferation of cancer cells. This medicine inhibits the proliferation and induces apoptosis (planned cell death) in bcr-abl positive cells (cancer cells). This is how it works to stop or slow the spread of cancer.
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Imanib 400mg Tablet. Please consult your doctor.
CONSULT YOUR DOCTOR
Imanib 400mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Imanib 400mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Lactating women should not breastfeed while using this drug and one month after stopping it.
Imanib 400mg Tablet may cause side effects which could affect your ability to drive.
Imanib 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Imanib 400mg Tablet may be needed. Please consult your doctor.
Imanib 400mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Imanib 400mg Tablet may be needed. Please consult your doctor.
Imanib 400mg Tablet is not recommended for use in children and adolescents below 18 years.
Imanib 400mg Tablet Habit Forming : NO
WHAT IF YOU FORGET TO TAKE IMANIB TABLET?
If you miss a dose of Imanib 400mg Tablet, skip it and continue with your normal schedule. Do not double the dose
- Always take it with food and a full glass of water to prevent nausea.
- It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
- Water retention and swelling are very common side effects of Imanib 400mg Tablet. Notify your doctor if you have unexpected rapid weight gain.
- Do not change the dose or discontinue use without consulting your doctor.
- Notify your doctor about all the medications you are taking, including over the counter medicines and dietary supplements.
- Your doctor may get regular blood tests done to monitor your liver function and the number of blood cells in your blood.
FOOD AND DRINK
- Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
- Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
- Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
- Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
- Drink more fluids and avoid alcoholic beverages to prevent dehydration.
Wash your hands properly before and after eating.
- Make sure you sleep at least 8 hours a day.
FAQs ABOUT IMANIB 400MG TABLET
Q: What happens if I stop taking IMANIB 400MG TABLET on my own?
A: Do not stop taking IMANIB 400MG TABLET unless your doctor tells you to stop even if the condition improves. If you are not able to take the IMANIB 400MG TABLET as your doctor prescribed or feel you do not need it anymore, contact your doctor immediately.
Q: It is safe to drive after taking IMANIB 400MG TABLET?
A: In some patients IMANIB 400MG TABLET may cause dizziness, drowsiness or blurred vision. So, it is better to avoid driving or operating any machine after taking IMANIB 400MG TABLET. Consult your doctor for advice before taking it.
Q: Can I take IMANIB 400MG TABLET during pregnancy?
A: IMANIB 400MG TABLET is generally not recommended for use in pregnant women unless advised by the doctor. Women who might become pregnant are advised to use effective contraceptive measures during treatment and for 15 days after ending the treatment. Consult your doctor before taking this medicine.
Q: How does IMANIB 400MG TABLET work?
A: IMANIB 400MG TABLET is a protein-tyrosine kinase inhibitor. Tyrosine kinases are proteins which act as chemical messengers that are used by the cancer cells to signal each other for their growth, therefore this medicine works by blocking the enzyme which stops the cancer cells from growing.
Q: Can IMANIB 400MG TABLET be used in patients with liver problems?
A: IMANIB 400MG TABLET should be used with caution in patients with liver problems and hepatitis B infection. Your doctor may monitor your liver function during and after treatment with this medicine to prevent the risk of any unusual effects. Consult your doctor before taking it.
- Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville. Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018 Page – 1203-1236.
- Nida Iqbal and Naveed Iqbal. Imatinib: A Breakthrough of Targeted Therapy in Cancer. Journal of chemotherapy research and practice. May 2014. [Accessed on 19th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055302/
- Andreas Hochhaus, Richard A. Larson, François Guilhot, Jerald P. Radich, Susan Branford, Timothy P. Hughes, Michele Baccarani, Michael W. Deininger, Francisco Cervantes, Satoko Fujihara, Christine-Elke Ortmann, Hans D. Menssen, et al. Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia. The New England of Medicine. March 2017. [Accessed on 19th November 2022] https://www.nejm.org/doi/full/10.1056/nejmoa1609324
- Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in August 2022] [Accessed on 19th November 2022] https://www.medicines.org.uk/emc/files/pil.2289.pdf
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