Myelostat 500mg Capsule

120.00

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Description

Last Updated on January 12, 2024 by admin

Myelostat 500 Overviwe

Myelostat 500mg Capsule is used in the treatment of some kinds of cancer and to prevent painful episodes associated with sickle cell anemia. It may be also used to treat some other conditions. It is sometimes used with certain other medicines as part of combination chemotherapy.

Myelostat 500mg Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include hematological disorders, gastrointestinal symptoms, eating disorders, and weight loss. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Salt Composition : Hydroxyurea 500mg

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

USES OF Myelostat 500

  • Ovarian cancer
  • Polycythemia vera
  • Chronic myeloid leukemia
  • Cervical cancer
  • Head and neck cancer
  • Sickle cell anemia

BENEFITS OF Myelostat 500

Head and neck cancer includes cancer of the mouth, nose, sinuses or throat. Myelostat 500mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.
Sickle cell anemia is a disorder of the red blood cells (RBCs) in which they lose their original round shape and flexibility, turn sickle shape and eventually die out. Myelostat 500mg Capsule makes your red blood cells bigger. It helps them stay rounder and more flexible and makes them less likely to turn into a sickle shape. The medicine does this by increasing a special kind of hemoglobin called hemoglobin F. Hemoglobin F is also called fetal hemoglobin because newborn babies have it. This helps to treat this disease and also prevents further complications that may be life-threatening.

More Information about Myelostat 500

  • Myelostat 500mg Capsule should be stored at room temperature between 68°F to 77°F (20°C to 25°C).
  • Keep in the original package.
  • Keep away from light, moisture, and heat.
  • Keep it away from children and pets.

SIDE EFFECTS OF Myelostat 500

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Myelostat 500

  • Hematological disorder
  • Gastrointestinal disorder
  • Eating disorder
  • Azoospermia (absence of sperms)
  • Decreased appetite
  • Fever
  • Oligospermia (low sperm count)
  • Skin cancer
  • Bone marrow suppression
  • Hallucination
  • Convulsion
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Pulmonary fibrosis
  • Pulmonary edema
  • Pancreatic inflammation
  • Liver toxicity
  • Cutaneous vasculitis
  • Increased uric acid level in blood

HOW TO USE Myelostat 500

Take this medicine in the dose and duration as advised by your doctor. Myelostat 500mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

HOW Myelostat 500 WORKS

In cancer, Myelostat 500mg Capsule works by blocking an enzyme (ribonucleotide reductase) which is required for synthesis of DNA. This prevents the cancer cells from growing and multiplying. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, improves blood flow and protects against complications such as painful sickle cell episodes.

SAFETY ADVICE

alcohol warning

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Myelostat 500mg Capsule. Please consult your doctor.
Pregnancy care

Pregnancy

CONSULT YOUR DOCTOR
Myelostat 500mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR
Myelostat 500mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE
Myelostat 500mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
kidney warning

Kidney

CAUTION
Myelostat 500mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Myelostat 500mg Capsule may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.

Liver

CAUTION
Myelostat 500mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Myelostat 500mg Capsule may be needed. Please consult your doctor.

baby warning   CHILDREN CAUTION
UNSAFE
Myelostat 500mg Capsule is not recommended for use in children and adolescents below 18 years.

  Myelostat 500mg Capsule Habit Forming :  NO

   expert advice

All substitutes

Quick tips
  • Take it at the same time every day, either with or without food.
  • It is advisable to stay hydrated and drink plenty of fluids while taking Myelostat 500mg Capsule.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.

Fact Box

Chemical Class – Anti Metabolites, {Urea}
Therapeutic Class – ANTI NEOPLASTICS
Action Class – Anti-cancer-others

1. Ovarian cancer

2. Polycythemia vera

3. Chronic myeloid leukemia

4. Cervical cancer

5. Head and neck cancer

6. Sickle cell anemia

References:

  1. Bristol-Myers Squibb Pharmaceuticals Unlimited Company, Electronic medicines compendium (EMC), [Revised on August 2021] [ Accessed on 17 April 2023], https://www.medicines.org.uk/emc/files/pil.271.pdf
  2. Bristol-Myers Squibb Company, US Food and Drug Administration, [Revised on March 2016] [ Accessed on 17th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016295Orig1s047,s048Lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1721.
  4. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 868.
  5. Rohit Kumar Agarwal et al; Hydroxyurea in Sickle Cell Disease: Drug Review; Indian Journal of Hematology & Blood Transfusion; Published on June 2014; Accessed on 17 April 2023; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022916/#__ffn_sectitle
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