Spegra Tablet

Last Updated on May 29, 2023 by admin

Buy Spegra Tablet Online

About Spegra Tablet

Dolutegravir (50mg) + Emtricitabine (200mg) + Tenofovir Alafenamide (25mg)

PRODUCT INTRODUCTION
Spegra Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

Spegra Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these Spegra Tablet regularly at the same time increases their effectiveness. A dose of this Spegra Tablet should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

The most common side effects of this Spegra Tablet are insomnia, fatigue, headache, and nausea. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

USES OF SPEGRA TABLET

• HIV infection

BENEFITS OF SPEGRA TABLET

• In HIV infection

Spegra Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life. This Spegra Tablet is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this Spegra Tablet as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of Spegra Tablet and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.

SIDE EFFECTS OF SPEGRA TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the Spegra Tablet. Consult your doctor if they persist or if you’re worried about them

Common side effects of Spegra

• Insomnia (difficulty in sleeping)
• Headache
• Nausea
• Fatigue

Severe side effects of Spegra

• Renal impairment
• Liver toxicity
• Hypersensitivity
• Worsening of hepatitis B (viral infection of liver)
• Immune reconstitution syndrome
• Lactic acidosis
• Hepatomegaly (enlarged liver)
• Anxiety

When SPEGRA not to use?

• Allergy
  Spegra Tablet is not recommended for use in patients with a known allergy to dolutegravir, emtricitabine, tenofovir alafenamide, or any other inactive ingredients present in the formulation.
• Dofetilide
  Spegra Tablet is not recommended for use in patients receiving dofetilide as it may increase the undesired effects of dofetilide which may lead to potentially serious and life-threatening side effects.

HOW TO USE SPEGRA TABLET

Take this Spegra Tablet in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spegra Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW SPEGRA TABLET WORKS

Spegra Tablet is a combination of three medicines: Dolutegravir, Emtricitabine and Tenofovir Alafenamide. It is an anti-HIV medication and works by preventing the action of reverse transcriptase enzyme. This enzyme is responsible for production of HIV.

Spegra Tablet Dosage

• Missed Dose
  Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra Spegra Tablet to make up for the missed dose.
• Overdose
  Seek emergency medical treatment or contact the doctor in case of an overdose.

General warnings

• Lactic acidosis
  Spegra Tablet should be used with caution due to the increased risk of lactic acidosis. Report any unusual symptoms to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.
• Decreased bone mineral density
  Spegra Tablet should be used with caution due to the increased risk of decreased bone mineral density. Report any unusual symptoms to the doctor on priority. Close monitoring of bone mineral density, appropriate corrective measures, and dose adjustments may be required in some cases based on the clinical condition
• Immune reconstitution syndrome
  Spegra Tablet should be used with caution due to the increased risk of Immune reconstitution syndrome. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
• Hypersensitivity reactions
  Spegra Tablet may cause severe allergic reactions such as skin rash, organ dysfunction, liver injury, etc. in some patients on therapy. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
• Fat redistribution
  Spegra Tablet may cause fat gain or fat loss from the body. This may result in peripheral wasting, facial wasting, breast enlargement, and Cushingoid appearance. Close monitoring of body weight and body fat distribution is necessary while receiving this medicine. Any changes in the body should be informed to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
• Opportunistic infections
  The patients receiving Spegra Tablet may develop opportunistic infections such as pneumonia, herpes virus infections, etc. Report any unusual symptoms to the doctor immediately. Appropriate patient/caregiver education, corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
• SAFETY ADVICE

warnings

   Alcohol CAUTION

Caution is advised when consuming alcohol with Spegra Tablet. Please consult your doctor.

warnings

   Pregnancy CAUTION

SAFE IF PRESCRIBED

Spegra Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

warnings

   Breastfeeding CAUTION

CONSULT YOUR DOCTOR

Information regarding the use of Spegra Tablet during breastfeeding is not available. Please consult your doctor.

warnings

   Driving CAUTION

CONSULT YOUR DOCTOR

It is not known whether Spegra Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

warnings

   Kidney CAUTION

UNSAFE

Spegra Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

warnings

   Liver CAUTION

UNSAFE

Spegra Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

warning

  CHILDREN CAUTION
UNSAFE
Spegra Tablet is not recommended for use in children and adolescents below 18 years.

   Spegra Tablet Habit Forming :  NO

   expert advice

• Spegra Tablet is given to slow the progress of HIV infection.
• Although treatment with Spegra Tablet can reduce the risk of you passing HIV to others through sexual contact, it does not stop it. It is therefore important to use condoms.
• If you develop any infection soon after taking Spegra Tablet, inform your doctor. As a result of taking Spegra Tablet, your immune system may start fighting an infection that was present before you started the treatment, but you might not be aware of.
• It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
• It is common for people with HIV to feel low or even depressed, especially soon after the diagnosis has been made.
• If you have any feelings of depression it is advisable to speak with your doctor.

   FOOD AND DRINK

• Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruit as it helps to boost your immune system. Option for lean protein and whole grains.
• Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
• Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
• Try to reduce emotional and physical stress by spending time with family or whatever makes you happy.
• Drink more fluids and avoid alcoholic beverages to prevent dehydration.
  Wash your hands properly before and after eating.
• Make sure you sleep at least 8 hours a day.

FAQs ABOUT SPEGRA TABLET

Q: Does Spegra Tablet cure HIV infection?

A: Spegra Tablet does not completely cure HIV infection. While taking this medicine, you may still develop infections or other diseases associated with HIV infection. Consult your doctor for advice.

Q: Is Spegra Tablet safe in pregnancy?

A: Before taking Spegra Tablet, inform your doctor if you are pregnant, think you may be pregnant or are planning to get pregnant because it may harm your unborn baby. Consult your doctor before taking Spegra Tablet.

Q: Can SPEGRA TABLET be used on children?

A: Your doctor will prescribe the right dose depends on your child’s age, body weight and disease condition. Consult your doctor before taking Spegra Tablet.

Q: What if I miss a dose of SPEGRA TABLET?

A: If you miss a dose of Spegra Tablet, take it as soon as you remember. However, omit the missed dose if it is almost time for the next dose. Do not take Spegra Tablet twice to make up for a forgotten dose.

Q: Can I stop taking SPEGRA TABLET?

A: Do not stop taking Spegra Tablet without consulting your doctor. If you have any more doubts regarding the use of Spegra Tablet, ask your doctor.

References

1. Dolutegravir – DrugBank [Internet]. Drugbank.ca. 2018 [cited 26 December 2018]. Available from:
   https://www.drugbank.ca/drugs/DB08930
2. Dolutegravir: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited 27 March 2019]. Available from:
   https://medlineplus.gov/druginfo/meds/a613043.html
3. Emtricitabine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 21 March 2018]. Available from:
   https://medlineplus.gov/druginfo/meds/a604004.html
4. Emtricitabine – DrugBank [Internet]. Drugbank.ca. 2018 [cited 21 March 2018]. Available from:
   https://www.drugbank.ca/drugs/DB00879
5. Tenofovir alafenamide – DrugBank [Internet]. Drugbank.ca. 2018 [cited 21 December 2018]. Available from:
   https://www.drugbank.ca/drugs/DB09299
6. [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 21 December 2018]. Available from:
   https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=72e6b33c-0351-4070-9172-eeaa186c01d2

Substitutes for Spegra Tablet

Alafevir De Tablet