Last Updated on January 29, 2024 by admin
Buy Spnib 50mg Tablet
Spnib 50mg Tablet Introduction
Spnib 50mg tablet is a medication that is commonly prescribed for the treatment of certain types of cancer, including chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). It belongs to a class of drugs called tyrosine kinase inhibitors, which work by blocking the action of abnormal proteins that promote the growth of cancer cells.
Use of Spnib 50mg Tablet
- Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body’s ability to fight infection. Spnib 50 Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Spnib 50mg tablet is also used to treat adults and children with CML and ALL who have not responded to or cannot tolerate other treatments. It is also used to treat adults with certain types of advanced or metastatic cancers, such as gastrointestinal stromal tumors (GIST) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL).
Benefits of Spnib 50mg Tablet
The main benefit of Spnib 50mg tablet is its ability to slow down or stop the growth of cancer cells. By inhibiting the activity of specific proteins, it helps to prevent the spread of cancer and improve the overall survival rate of patients. Additionally, Spnib 50mg tablet has been shown to reduce the size of tumors and alleviate symptoms associated with certain types of cancer.
Side Effects of Spnib 50mg Tablet
Like any medication, Spnib 50mg tablet can cause side effects. Common side effects include nausea, diarrhea, headache, fatigue, and skin rash. In some cases, more serious side effects may occur, such as low blood cell counts, bleeding, heart problems, and lung complications. It is important to discuss any concerns or unusual symptoms with your healthcare provider.
Drug Warnings for Spnib 50mg Tablet
Prior to starting Spnib 50mg tablet, it is important to inform your healthcare provider about any existing medical conditions or allergies you may have. This medication may not be suitable for individuals with a history of heart disease, liver problems, or bleeding disorders. It is also important to avoid grapefruit or grapefruit juice while taking Spnib 50mg tablet, as it can increase the risk of side effects.
Drug Interactions with Spnib 50mg Tablet
Spnib 50mg tablet may interact with other medications, including certain antibiotics, antifungals, and antivirals. It is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. This will help to prevent any potential drug interactions and ensure the safe and effective use of Spnib 50mg tablet.
Directions for Use of Spnib 50mg Tablet
Spnib 50mg tablet should be taken exactly as prescribed by your healthcare provider. It is usually taken once or twice daily, with or without food. The tablets should be swallowed whole with a glass of water and should not be crushed or chewed. If you have difficulty swallowing the tablets, speak to your healthcare provider for alternative options.
How to Take Spnib 50mg Tablet
It is important to follow the instructions provided by your healthcare provider on how to take Spnib 50mg tablet. If you have any questions or concerns, do not hesitate to ask your healthcare provider or pharmacist for clarification. They can provide you with additional information on the proper administration of Spnib 50mg tablet.
Storage of Spnib 50mg Tablet
Spnib 50mg tablet should be stored at room temperature, away from direct sunlight and moisture. Keep the medication in its original packaging and out of reach of children and pets. Do not use Spnib 50mg tablet if it has expired or if the packaging is damaged.
How Spnib 50mg Tablet Works
Spnib 50mg tablet works by inhibiting the activity of specific proteins known as tyrosine kinases. These proteins are involved in the growth and survival of cancer cells. By blocking their action, Spnib 50mg tablet helps to slow down or stop the growth of cancer cells, ultimately leading to the destruction of the tumor.
Safety Advice for Spnib 50mg Tablet
When taking Spnib 50mg tablet, it is important to follow these safety precautions:
- Take the medication exactly as prescribed by your healthcare provider.
- Do not adjust the dosage or stop taking the medication without consulting your healthcare provider.
- Inform your healthcare provider about any existing medical conditions or allergies.
- Attend all scheduled medical appointments and laboratory tests to monitor your response to the medication.
- Avoid activities that may increase the risk of bleeding or injury.
- Report any unusual side effects or symptoms to your healthcare provider immediately.
SIDE EFFECTS OF Spnib 50mg TABLET
COMMON
- Increased infections
- Nausea, vomiting
- Diarrhea, stomach pain, bloating, constipation, heartburn
- Lack of appetite, changes in taste
- Mouth ulcers, hair loss
- Weight loss or weight gain
- Headache, tiredness, weakness
- Dizziness
- Skin rash, itching, dry skin, acne
- Increased bleeding tendency
- Joint pain, muscle pain or spasms
- Increased sweating, flushing
- Blurred vision, dry eyes
- Depression, sleeplessness
- Oedema (swelling of body parts)
- Irregular heartbeat, chest pain, breathing difficulties
- Stomach ulcers, inflammation of the food pipe
- Swollen tummy, anal tears
- Anxiety, confusion, mood swings, memory loss
- Low sexual drive
- Loss of hearing, sensitivity to light
- Skin inflammation, nail disorder
- Problems in passing urine
- Breast enlargement in men, menstrual disorder
- High blood cholesterol levels
- Swollen lymph nodes
- Increased protein in the urine
Stop taking Spnib 50mg TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- Signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- Chest pain, cough, breathing difficulties and fainting (signs of fluid retention in lungs)
- Unusual bleeding or bruising with fever, tiredness and confusion (signs of blood vessel damage)
- Bloody stools/urine/vomit or black tarry stools
- Blistering or peeling of skin and mucous membranes with fever and sore throat, mouth ulcers
WARNING & PRECAUTIONS
PREGNANCY
CONTRAINDICATED
Spnib 50mg TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before taking Spnib 50mg TABLET if you are pregnant or think you may be pregnant. Women of childbearing potential must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with Spnib 50mg .
BREASTFEEDING
CONTRAINDICATED
Spnib 50mg TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Therefore, consult your doctor taking it.
DRIVING AND USING MACHINES
USE WITH CAUTION
Do not drive or operate any heavy tools or machines if you feel dizzy after taking Spnib 50mg TABLET.
ALCOHOL
CONSULT YOUR DOCTOR
Avoid consumption of alcohol while taking Spnib 50mg TABLET as it could make you feel dizzier.
KIDNEY
USE WITH CAUTION
Spnib 50mg TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
LIVER
USE WITH CAUTION
Spnib 50mg TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
CHILDREN CAUTIONUNSAFE
Spnib 50mg Tablet is not recommended for use in children and adolescents below 18 years.
HEART DISEASE
USE WITH CAUTION
Spnib 50mg TABLET should be used with caution in patients with heart problems. Therefore, consult your doctor before taking it.
OTHERS
Spnib 50mg TABLET is not recommended for use if you:
- Have, ever had or at risk of having hepatitis B infection
INTERACTIONS
Spnib 50mg -Drug Interactions:
Before taking Spnib 50mg TABLET, inform your doctor, if you are taking any of the following medicines such as:
- Medicines used for blood thinning (Ex. warfarin)
- Ketoconazole, itraconazole (used to manage fungal infection)
- Medicines used to manage bacterial infection (such as erythromycin, clarithromycin, telithromycin)
- Ritonavir (a medicine used to manage HIV infection)
- Medicines used to manage epilepsy (Ex. phenytoin, carbamazepine, phenobarbital)
- Rifampicin (a medicine used to manage tuberculosis)
- Medicines used to manage stomach ulcers (such as famotidine, omeprazole)
- St. John’s wort (an herbal preparation used to manage depression)
- Antacids (used to neutralize stomach acids) Ex. aluminium hydroxide or magnesium hydroxide
Spnib 50mg -Food Interactions:
Avoid eating grapefruit or drinking grapefruit juice while taking Spnib 50mg TABLET as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally took more Spnib 50mg TABLET, consult your doctor immediately or visit the nearby hospital.
Special Advice for Spnib 50mg Tablet
It is important to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding while taking Spnib 50mg tablet. This medication may not be safe during pregnancy or while breastfeeding, and your healthcare provider can provide you with guidance on the potential risks and benefits.
Other Information about Spnib 50mg Tablet
Spnib 50mg tablet is a prescription medication and should only be used under the supervision of a healthcare provider. It is important to read the patient information leaflet provided with the medication for additional information on proper use, storage, and potential side effects. If you have any questions or concerns, do not hesitate to reach out to your healthcare provider or pharmacist.
FAQs ABOUT Spnib 50mg TABLET
Q: What is Spnib 50mg TABLET used for?
A: Spnib 50mg TABLET is used to manage cancers of blood and bone marrow (such as chronic myeloid leukaemia (CML) and philadelphia chromosome positive (Ph+) acute lymphoblastic leukaemia) in adults, adolescents and in children (aged 1 year or above). It is primarily used in patients when management with conventional therapies is not suitable or fails to provide adequate response.
Q: How Spnib 50mg TABLET works in my body?
A: Spnib 50mg TABLET is an anti-cancer medicine. It works by blocking the actions of certain proteins (such as BCR-ABL, Src kinase, etc.) in the body that triggers cancer formation. As a result, it reduces abnormal growth and multiplication of cancer cells in the body.
Q: Can Spnib 50mg TABLET cure cancer?
A: The success rate of cancer depends upon the severity of the disease. However, Spnib 50mg TABLET acts by stopping the abnormal growth and multiplication of cancer cells in the body, which may help in managing the cancer completely.
Q: Can the use of Spnib 50mg TABLET cause hair loss?
A: Hair loss is one of the common side effects of taking Spnib 50mg TABLET. If it bothers you, consult your doctor for advice.
Q: Can the use of Spnib 50mg TABLET cause mouth ulcers?
A: Mouth ulcers are one of the common side effects of taking Spnib 50mg TABLET. Avoid eating spicy foods. Drink plenty of water. Apply a pain-relieving gel on the affected areas of the mouth if required. Consult your doctor if the symptom did not improve
Q: Can Spnib 50mg TABLET be used in children?
A: Spnib 50mg TABLET can be used in children and adolescents (aged 1 year or above) if prescribed by the physician. It should not be used in children aged below 1 year due to increased risk of side effects.
Q: Is Spnib 50mg TABLET a chemo drug?
A: Yes. Spnib 50mg TABLET contains a medicine called Dasatinib which is a chemotherapeutic agent. It stops abnormal growth and multiplication of cancer cells in the body.
Q: What happens if I forgot to take a dose of Spnib 50mg TABLET?
A: If you forgot to take a dose of Spnib 50mg TABLET, take it as soon as you remember. However, if it is time for the next dose of Spnib 50mg TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of Spnib 50mg TABLET to compensate the missed ones.
Q: What precautions must be followed while taking Spnib 50mg TABLET?
A: Before taking Spnib 50mg TABLET inform your doctor if you have any liver, kidney or heart problems or if you have or at risk of developing hepatitis C infection as a precaution. Avoid eating grapefruit or drinking grapefruit juice while taking Spnib 50mg TABLET. Leave a time gap of at least 2 hours between Spnib 50mg TABLET and stomach medicines. Inform your doctor before taking Spnib 50mg TABLET if you are pregnant or breastfeeding women. Men and women taking Spnib 50mg TABLET must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with Spnib 50mg TABLET.
Q: Will taking a higher dose of Spnib 50mg TABLET be more effective?
A: No, taking a higher dose of Spnib 50mg TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy
Q: What happens if I stop taking Spnib 50mg TABLET?
A: No. Do not stop taking Spnib 50mg TABLET without consulting your doctor as it may make your symptoms reappear. Therefore, take Spnib 50mg TABLET as advised by your doctor for the stipulated duration.
Q: Can Spnib 50mg TABLET be used during pregnancy?
A: Spnib 50mg TABLET is not recommended for use in pregnant women unless considered necessary by the physician. Therefore, inform your doctor before taking Spnib 50mg TABLET if you are pregnant or think you may be pregnant.
Q: Can the use of Spnib 50mg TABLET make me feel tired?
A: Yes. Spnib 50mg TABLET may make you feel tired easily. This is because, it reduces the levels of red blood cells in your blood and may make you anaemic. Consult your doctor if you experience tiredness after taking Spnib 50mg TABLET. Tiredness can also occur if you have any pre-existing disease conditions such as liver or kidney impairment while taking this medicine.
Q: Can I drive a car after taking Spnib 50mg TABLET?
A: Spnib 50mg TABLET may make you feel tired or dizzy. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by Spnib 50mg TABLET.
Q: How to take Spnib 50mg TABLET?
A: Take Spnib 50mg TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Spnib 50mg TABLET can be taken with or without food.
Q: How to control nausea caused due to Spnib 50mg TABLET?
A: Generally, anticancer medicines are associated with uncontrollable nausea and vomiting. To avoid this, your doctor would prescribe a suitable medicine to control them along with Spnib 50mg TABLET. If not, consult your doctor for a suitable anti-emetic medicine. Do not self-manage nausea.
Q: What are the side effects of taking Spnib 50mg TABLET?
A: The most common side effects of taking Spnib 50mg TABLET are increased bleeding tendency, increased infections, feeling tired or weak, nausea, vomiting, hair loss, mouth ulcers, changes in taste, inflammation of the food pipe or stomach, muscle pain or spasm, skin rashes, headache, dizziness and weight loss. Contact your doctor if any of these side effect worsens.
Q: Who should avoid taking Spnib 50mg TABLET?
A: Spnib 50mg TABLET is not recommended for use if you are allergic to dasatinib. It is also not recommended for use in pregnant or breastfeeding women and in children (aged below 1 year).
Q: Is Spnib 50mg TABLET safe to use in kidney disease?
A: Spnib 50mg TABLET should be used with caution in patients with kidney problems. Your doctor will access your health condition and suggest a suitable dose for you.
Q: Can the use of Spnib 50mg TABLET affect the liver?
A: Yes. Spnib 50mg TABLET may affect the way your liver work. It can elevate the levels of certain liver enzymes in your body. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.
Q: what is Spnib 50mg tablet price?
A: Spnib 50mg Tablet is available at net rate 2,599 on HIVHUB.IN, which provides free shipping all over India and also gives cash on delivery, MRP of Spnib 50mg in the market is 3,095.
REFERENCES:
- Laurence Brunton. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies and Cytokines. Goodman and Gillman’s: The Pharmacological Basics of Therapeutics. Twelfth Edition. 2011. Page – 1732-1734.
- Dilek Keskin, Sevil Sadri, Ahmet Emre Eskazan. Dasatinib for the treatment of chronic myeloid leukemia: patient selection and special considerations. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. October 2016. [Assessed on 10th November 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066856/
- Zentiva Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in May 2022]. [Accessed on 10th November 2022] https://www.medicines.org.uk/emc/files/pil.10921.pdf
- Bristol-Myers Squibb Pharma EEIG. Electronic Medicines Compendium (EMC). [Revised in March 2022]. [Accessed on 10th November 2022] https://www.medicines.org.uk/emc/files/pil.3958.pdf
- Bristol-Myers Squibb Canada. SPRYCEL. [Revised in November 2021] [Assessed on 10th November 2022] https://www.bms.com/assets/bms/ca/documents/productmonograph/SPRYCEL_EN_PM.pdf
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