Last Updated on April 23, 2023 by admin
Lazid N Tablet
Lamivudine (150mg) + Zidovudine (300mg) + Nevirapine (200mg)
Lazid N Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
Lazid N Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.
The most common side effects of this medicine are headaches, nasal congestion, diarrhea, nausea, weakness and tiredness, cough, and rash. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated.
Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.
USES OF LAZID N TABLET
BENEFITS OF LAZID N TABLET
Lazid N Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.
It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.
SIDE EFFECTS OF LAZID N TABLET
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lazid N
- Insomnia (difficulty in sleeping)
- Decreased white blood cell count (neutrophils)
- Gastrointestinal disturbance
- Hair loss
- Joint pain
- Muscle disorders
- General discomfort
HOW TO USE LAZID N TABLET
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lazid N Tablet may be taken with or without food, but it is better to take it at a fixed time.
HOW LAZID N TABLET WORKS
Lazid N Tablet is a combination of three antiviral medicines: Lamivudine, Zidovudine and Nevirapine. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.
Caution is advised when consuming alcohol with Lazid N Tablet. Please consult your doctor.
CONSULT YOUR DOCTOR
Lazid N Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SAFE IF PRESCRIBED
Lazid N Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Lazid N Tablet may cause side effects which could affect your ability to drive.
You may experience fatigue while taking Lazid N Tablet and this may affect your ability to drive.
Lazid N Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lazid N Tablet may be needed. Please consult your doctor.
Lazid N Tablet should be used with caution in patients with liver disease. Dose adjustment of Lazid N Tablet may be needed. Please consult your doctor.
Use of Lazid N Tablet is not recommended in patients with moderate to severe liver disease. Regular monitoring of liver function tests is advised while you are taking this medicine.
Lazid N Tablet is not recommended for use in children and adolescents below 18 years.
Lazid N Tablet Habit Forming : NO
WHAT IF YOU FORGET TO TAKE LAZID N TABLET?
If you miss a dose of Lazid N Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
- Lazid N Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
- Take it on an empty stomach, preferably at bedtime, to reduce side effects.
- Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
- Lazid N Tablet may cause dizziness or sleepiness. Don’t drive or do anything requiring concentration until you know how it affects you.
- Lazid N Tablet can cause birth defects. Use effective contraception while taking Lazid N Tablet and 12 weeks after stopping it.
- It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
- Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
- Do not stop taking Lazid N Tablet without your doctor’s advice.
FAQs ABOUT LAZID N TABLET
Q: Are women more prone to LAZID N TABLET side effects?
A: Women with CD4 counts more than 250 cells/mm3 are at a greater risk of having liver side effects and lactic acidosis with LAZID N TABLET. Consult your doctor before taking it.
Q: Can I develop rashes while taking LAZID N TABLET?
A: Skin rash is the most common side effect of LAZID N TABLET. Rashes can turn serious, so stop taking this medicine and go to your doctor the moment you develop a rash.
Q: Do I have more chances of getting side effects with LAZID N TABLET if I am overweight?
A: You might have more chances of getting a side effect called lactic acidosis with LAZID N TABLET if you are overweight. Consult your doctor before taking it.
Q: Can I drink alcohol with LAZID N TABLET?
A: Consuming alcohol with LAZID N TABLET may put you at a greater risk of developing a bone problem called osteonecrosis (bone cell death), so it is better to avoid it. Consult your doctor for further queries.
Q: How does LAZID N TABLET cure HIV infection?
A: LAZID N TABLETdoes not cure HIV infection. It reduces the amount of HIV virus in your body and increase CD4 cell counts (a type of white blood cell, which is important in maintaining a healthy immune system. It is important that you remain under the care of your doctor.
Q: Can LAZID N TABLET be taken in pregnancy?
A: LAZID N TABLET should be used in pregnant women only if considered necessary by your doctor. If you are pregnant, think you may be during pregnancy or are planning to get pregnant, consult your doctor before taking it. Inform your doctor immediately if you become pregnant during treatment with LAZID N TABLET.
Q: Can I still pass HIV to other during LAZID N TABLET treatment?
A: LAZID N TABLET does not lower the risk of passing HIV to other people. For yours and other health, it is important to take appropriate precautions. Ask your doctor about the preventive measures that you can take.
Q: Can LAZID N TABLET be crushed?
A: No. Do not chew, crush or split LAZID N TABLET. Simply swallow it wholly, with a glass of water.
Q: What if I vomit out LAZID N TABLET?
A: If you vomit out LAZID N TABLET, take another medicine. Do not wait until the next dose is scheduled.
Q: Can LAZID N TABLET change my body shape?
A: Treatment with LAZID N TABLET might cause redistribution, accumulation, or loss of body fat, which might lead to a change in your body shape. Contact your doctor if you notice any such changes.
Q: Can LAZID N TABLET be used on infants?
A: No. LAZID N TABLET is not recommended for use in children (weighing less than 25 kgs). Your doctor will decide the correct dose or select a suitable alternative therapy for your child.
Q: What if I miss a dose of LAZID N TABLET?
A: If you miss a dose of LAZID N TABLET, take it if you remember within 6 hours of missing the dose. However, omit if it is more than 6 hours past the missed dose. Do not take LAZID N TABLET twice to make up for a forgotten dose.
- KD. Tripathi. Antiviral drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 813.
- Anderson PL, Rower JE. Zidovudine and Lamivudine for HIV Infection. NIH National Library of Medicine, National centre for biotechnology information. PubMed central. October 2010. [Accessed on 4th July 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954111/
- Nabila Rehman, Hoang Nguyen. Nevirapine. StatPearls [Internet]. StatPearls Publishing. July 2021. [Accessed on 4th July 2022] https://www.ncbi.nlm.nih.gov/books/NBK554477/#article-25853.s3
- Sun Pharmaceutical Industries Limited. Lamivudine + Nevirapine + Zidovudine. [Revised in July 2018] [Accessed on 4th July 2022] https://extranet.who.int/pqweb/sites/default/files/HA323part3.pdf
- Cipla Ltd. Lamivudine + Nevirapine + Zidovudine. [Revised in August 2020] [Accessed on 4th July 2022] https://www.ciplamed.com/content/duovir-n-tablets#patientcounselinginformation
Substitutes for Lazid N Tablet
Duovir N Tablet
Zidolam N Tablet 1*60